Serum Neutralization Assay Can Efficiently Replace Plaque Reduction Neutralization Test for Detection and Quantitation of West Nile Virus Antibodies in Human and Animal Serum Samples-Reference-Cited by-同舟云学术

Serum Neutralization Assay Can Efficiently Replace Plaque Reduction Neutralization Test for Detection and Quantitation of West Nile Virus Antibodies in Human and Animal Serum Samples

Published:2014-10 Issue:10 Volume:21 Page:1460-1462
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Di Gennaro Annapia¹,Lorusso Alessio¹,Casaccia Claudia¹,Conte Annamaria¹,Monaco Federica¹,Savini Giovanni¹

Affiliation:

1. OIE Reference Laboratory for West Nile Disease, Istituto Zooprofilattico Sperimentale dell'Abruzzo e Molise, G. Caporale, Teramo, Italy

Abstract

ABSTRACT A serum neutralization assay (SN) was compared with the official plaque reduction neutralization test for the quantitation of West Nile virus antibodies. A total of 1,348 samples from equid sera and 38 from human sera were tested by these two methods. Statistically significant differences were not observed, thus supporting the use of SN for routine purposes.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00426-14

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