In Situ Visualization of the pKM101-Encoded Type IV Secretion System Reveals a Highly Symmetric ATPase Energy Center-Reference-Cited by-同舟云学术

In Situ Visualization of the pKM101-Encoded Type IV Secretion System Reveals a Highly Symmetric ATPase Energy Center

Published:2021-10-26 Issue:5 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Khara Pratick¹,Song Liqiang¹,Christie Peter J.¹^ORCID,Hu Bo¹

Affiliation:

1. Department of Microbiology and Molecular Genetics, McGovern Medical School, Houston, Texas, USA

Abstract

Bacterial type IV secretion systems (T4SSs) play central roles in antibiotic resistance spread and virulence. By cryo-electron tomography (CryoET), we solved the structure of the plasmid pKM101-encoded T4SS in the native context of the bacterial cell envelope.

Funder

HHS | National Institutes of Health

Welch Foundation

National Science Foundation

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.02465-21

Reference66 articles.

1. Type IV secretion in Gram-negative and Gram-positive bacteria