Comparative In Vitro Evaluation of the Effects of Ticarcillin and Carbenicillin upon Pseudomonas aeruginosa

Author:

Kalkani E.1,Marketos N.1

Affiliation:

1. Department of Microbiology, National Hospital of Athens “King Paul”, Athens, Greece

Abstract

An in vitro comparison of the effects of ticarcillin and carbenicillin was performed upon 164 strains of Pseudomonas aeruginosa . The two drugs displayed nearly identical inhibitory activities: for each, about 82.5% of the strains were inhibited by doses of 256 μg/ml or less. A low bactericidal activity was also observed. Strains of P. aeruginosa that were highly resistant to carbenicillin were also resistant to ticarcillin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference7 articles.

1. Adler J. L. J. P. Burke C. Wilcox and M. Finland. 1971. Susceptibility of Proteus species and Pseudomonas aeruginosa to penicillins and cephalosporins p. 63-67. Antimicrob. Agents Chemother. 1970.

2. Carbenicillin therapy for pseudomonas infections;Bodey G. P.;J. Am. Med. Assoc.,1971

3. Typing of Pseudomonas pyocyanea by pyocine production;Gillies R. R.;J. Pathol. Bacteriol.,1966

4. Carbenicillin: clinical and laboratory experience with a parenterally administered penicillin for treatment of Pseudomonas infections;Neu H. C.;Ann. Intern. Med.,1969

5. Neu H. C. and E. B. Winshell. 1971. In vitro studies of a semisynthetic penicillin 6-[D(-)-a-carboxy-3-thienylacetamido] penicillanic acid (BRL 2288) active against Pseudomonas p. 385-389. Antimicrob. Agents Chemother. 1970.

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3