Affiliation:
1. Departments of Microbiology and Biology, University of Alabama in Birmingham, Birmingham, Alabama 35233
Abstract
Donor deoxyribonucleic acid extracted from streptomycin-resistant (Str
R
) mutant derivatives of a variety of strains of
Streptococcus mutans, S. salivarius
, and
S. sanguis
was used to transform streptomycin resistance into competent
S. sanguis
strain Challis. Transfer of genetic markers for sorbitol and mannitol fermentation and for extracellular polysaccharide as demonstrated by colonial morphology was not detected in this study. Reciprocal transformation between strain Challis and other oral streptococci could not be demonstrated. Transformation frequencies for Str
R
were relatively efficient among
S. sanguis
strains, with lower but significant frequencies demonstrated with strain Challis and donor deoxyribonucleic acid derived from other oral streptococci.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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