Affiliation:
1. Institut für Biologie III, Albert-Ludwigs-Universität Freiburg, Federal Republic of Germany.
Abstract
High-level expression of the Tn10 tetracycline resistance protein TetA in Escherichia coli caused partial collapse of the membrane potential, arrest of growth, and killing of the cells. Since alpha-methylglucoside transport was not affected, the overproduced TetA protein may cause not destruction of membrane structure but rather unrestricted translocation of protons and/or ions across the membrane.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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