camR, a negative regulator locus of the cytochrome P-450cam hydroxylase operon-Reference-Cited by-同舟云学术

camR, a negative regulator locus of the cytochrome P-450cam hydroxylase operon

Published:1986-06 Issue:3 Volume:166 Page:1089-1095
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Koga H,Aramaki H,Yamaguchi E,Takeuchi K,Horiuchi T,Gunsalus I C

Abstract

A 4.27-kilobase insert from a HindIII DNA library of Pseudomonas putida carrying the CAM plasmid allowed coordinate expression of genes camD and camC under control of camR, an upstream regulator. The camC gene specifies cytochrome P-450cam, and camD specifies the 5-exo-alcohol dehydrogenase. A 1.38-kilobase deletion from the insert results in the constitutive expression of genes camC and camD; transformation in trans restores the substrate control, indicating that camR is a negative regulator.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.166.3.1089-1095.1986

Reference43 articles.

1. The 14 a-demethylation of lanosterol by a reconstituted cytochrome P450 system from yeast microsomes;Aoyama Y.;Biochem. Biophys. Res. Commun.,1978

2. Microbiological degradation of (+)- camphor;Bradshaw W. H.;J. Am. Chem. Soc.,1959

3. The enzymatic hydroxylation of n-octane by Corynebacterium sp. strain 7E1C;Cardini G.;J. Biol. Chem.,1970

4. Identification and characterization of large plasmids in Rhizobium meliloti using agarose gel electrophoresis;Casse F.;J. Gen. Microbiol.,1979

5. Genetic basis of the biodegradation of salicylate in Pseudomonas;Chakrabarty A. M.;J. Bacteriol.,1972

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Degradative Plasmids;Plasmid Biology;2014-04-08

2. The TetR Family of Regulators;Microbiology and Molecular Biology Reviews;2013-09

3. Camphor Pathway Redux: Functional Recombinant Expression of 2,5- and 3,6-Diketocamphane Monooxygenases of Pseudomonas putida ATCC 17453 with Their Cognate Flavin Reductase Catalyzing Baeyer-Villiger Reactions;Applied and Environmental Microbiology;2013-05-15

4. Cloning, Baeyer-Villiger Biooxidations, and Structures of the Camphor Pathway 2-Oxo-Δ3-4,5,5-Trimethylcyclopentenylacetyl-Coenzyme A Monooxygenase of Pseudomonas putida ATCC 17453;Applied and Environmental Microbiology;2012-01-20

5. Formation of repressor-inducer-operator ternary complex: negative cooperativity of d-camphor binding to CamR;Genes to Cells;2011-11-17