Location of Genes for Motility and Chemotaxis on the Escherichia coli Genetic Map

Abstract

In Escherichia coli , the following genes are involved in motility and chemotaxis. The H gene is the structural gene for flagellin. Mutation in the mot gene results in paralysis of the flagella, and mutation in the fla genes leads to an absence of flagella. The cheA, cheB , and cheC genes are required for chemotaxis. The chromosomal location of these genes has now been determined. The majority are clustered in a small region around uvrC , between his and aroD , in the order his-cheC-H-uvrC-mot-cheA-cheB-aroD . The fla genes are located in the same region, and also between trp and gal . The results indicate that many of the genes are homologous to those which have been studied in Salmonella typhimurium .