Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung-Reference-Cited by-同舟云学术

Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung

Published:2022-11-17 Issue:11 Volume:90 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Bollar Gretchen E.¹²^ORCID,Keith Johnathan D.²,Oden Ashley M.¹,Kiedrowski Megan R.¹²,Birket Susan E.¹²^ORCID

Affiliation:

1. Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA

2. Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA

Abstract

Cystic fibrosis (CF) disease is characterized by lifelong infections with pathogens such as Staphylococcus aureus , leading to eventual respiratory failure. Small colony variants (SCVs) of S. aureus have been linked to worse clinical outcomes for people with CF.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

Cystic Fibrosis Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00237-22

Reference69 articles.

1. Cystic Fibrosis

2. Lung Infections Associated with Cystic Fibrosis