Molecular Analysis of Resistance and Detection of Non-Wild-Type Strains Using Etest Epidemiological Cutoff Values for Amphotericin B and Echinocandins for Bloodstream Candida Infections from a Tertiary Hospital in Qatar

Author:

Taj-Aldeen Saad J.12,Salah Husam13,Perez Winder B.4,Almaslamani Muna25,Motyl Mary6,AbdulWahab Atqah27,Healey Kelley R.4,Perlin David S.4

Affiliation:

1. Mycology Unit, Microbiology Division, Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar

2. Weill Cornell Medicine-Qatar, Doha, Qatar

3. CBS Fungal Biodiversity Centre, Utrecht, The Netherlands

4. Public Health Research Institute, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA

5. Department of Medicine, Hamad Medical Corporation, Doha, Qatar

6. Merck & Co., Inc., West Point, Pennsylvania, USA

7. Department of Pediatrics, Hamad Medical Corporation, Doha, Qatar

Abstract

A total of 301 Candida bloodstream isolates collected from 289 patients over 5 years at a tertiary hospital in Qatar were evaluated. Out of all Candida infections, 53% were diagnosed in patients admitted to the intensive care units.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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