Genetic Relationships among Multidrug-Resistant Salmonella enterica Serovar Typhimurium Strains from Humans and Animals-Reference-Cited by-同舟云学术

Genetic Relationships among Multidrug-Resistant Salmonella enterica Serovar Typhimurium Strains from Humans and Animals

Published:2018-05 Issue:5 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hong Yu-Ping¹,Wang You-Wun¹,Huang I-Hsiu²,Liao Yu-Chieh³^ORCID,Kuo Hung-Chih⁴,Liu Yen-Yi³,Tu Yueh-Hua¹,Chen Bo-Han¹,Liao Ying-Shu¹,Chiou Chien-Shun¹^ORCID

Affiliation:

1. Central Regional Laboratory, Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan

2. Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

3. Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan

4. Department of Veterinary Medicine, National Chiayi University, Chiayi, Taiwan

Abstract

ABSTRACT We identified 20 to 22 resistance genes, carried in four incompatibility groups of plasmids, in each of five genetically closely related Salmonella enterica serovar Typhimurium strains recovered from humans, pigs, and chickens. The genes conferred resistance to aminoglycosides, chloramphenicol, sulfonamides, trimethoprim, tetracycline, fluoroquinolones, extended-spectrum cephalosporins and cefoxitin, and azithromycin. This study demonstrates the transmission of multidrug-resistant Salmonella strains among humans and food animals and may be the first identification of mphA in azithromycin-resistant Salmonella strains in Taiwan.

Funder

Ministry of Health and Welfare, Taiwan

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00213-18

Reference23 articles.

1. An Association of Genotypes and Antimicrobial Resistance Patterns among Salmonella Isolates from Pigs and Humans in Taiwan

2. Multidrug resistance among different serotypes of clinical Salmonella isolates in Taiwan

3. Human isolates of Salmonella enterica serovar Typhimurium from Taiwan displayed significantly higher levels of antimicrobial resistance than those from Denmark