Type III 5-methylcytosine modification of DNA in Neisseria gonorrhoeae

Author:

Korch C,Hagblom P,Normark S

Abstract

We present here the first report of a type III methyltransferase that modifies a cytosine. Neisseria gonorrhoeae 82409/55 (pJD1) modifies the first cytosine on only one strand from the 5' end of the nonpalindromic sequence: (Formula; see text). We have called this modifying activity M X NgoVIII.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference7 articles.

1. Bickel T. A. 1982. The ATP-dependent restriction endonucleases p. 85-108. In S. M. Linn and R. J. Roberts (ed.) Nucleases. Cold Spring Harbor Laboratory Cold Spring Harbor N.Y.

2. Sequence-specific DNA modification in Neisseria gonorrhoeae;Korch C.;J. Bacteriol.,1983

3. Sequencing end-labeled DNA with base-specific chemical cleavages;Maxam A. M.;Methods Enzymol.,1980

4. Deoxyribonucleic acid modifications and restriction endonuclease production in Neisseria gonorrhoeae;Norlander L.;J. Bacteriol.,1981

5. Detection of 5-methylcytosine in DNA sequences;Ohmori H.;Nucleic Acids Res.,1978

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