Evaluation of the Rapid BioStar Optical Immunoassay for Detection of Chlamydia trachomatis in Adolescent Women

Author:

Bandea Claudiu I.1,Koumans Emilia H.2,Sawyer Mary K.3,Dover Jason1,O'Connor Angelica2,Papp John R.2,Unger Elizabeth R.1,Braxton Jim2,Black Carolyn M.1

Affiliation:

1. National Center for Infectious Diseases

2. National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention

3. Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia

Abstract

ABSTRACT We evaluated the performance of the BioStar Chlamydia OIA (optical immunoassay) in adolescent females ( n = 261) from an inner city population. With a reference standard of two different nucleic acid amplification tests, the sensitivity and specificity of the BioStar Chlamydia OIA were 59.4 and 98.4%, respectively. Due to its relatively low sensitivity, the BioStar Chlamydia OIA should only be used in conjunction with more sensitive laboratory tests unless laboratory tests are unavailable or timely return for treatment is unlikely.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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