Insertion Sequence (IS)-Excision Enhancer (IEE)-Mediated IS Excision from the <i>lacZ</i> Gene Restores the Lactose Utilization Defect of Shiga Toxin-Producing Escherichia coli O121:H19 Strains and Is Responsible for Their Delayed Lactose Utilization Phenotype-Reference-Cited by-同舟云学术

Insertion Sequence (IS)-Excision Enhancer (IEE)-Mediated IS Excision from the lacZ Gene Restores the Lactose Utilization Defect of Shiga Toxin-Producing Escherichia coli O121:H19 Strains and Is Responsible for Their Delayed Lactose Utilization Phenotype

Published:2022-08-23 Issue:16 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Nakamura Keiji¹^ORCID,Seto Kazuko²,Isobe Junko³,Taniguchi Itsuki¹,Gotoh Yasuhiro¹,Hayashi Tetsuya¹

Affiliation:

1. Department of Bacteriology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

2. Division of Planning, Osaka Institute of Public Health, Osaka, Japan

3. Department of Bacteriology, Toyama Institute of Health, Toyama, Japan

Abstract

Insertion sequences (ISs) can modulate gene expression by gene inactivation or activation. While phenotypic changes due to IS insertion/transposition are frequently observed, gene reactivation by precise or simple IS excision rarely occurs.

Funder

Japan Agency for Medical Research and Development

Ministry of Health, Labour and Welfare

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.00760-22

Reference38 articles.

1. Everyman's Guide to Bacterial Insertion Sequences

2. ISfinder: the reference centre for bacterial insertion sequences