Molecular Engineering of a Mammarenavirus with Unbreachable Attenuation-Reference-Cited by-同舟云学术

Molecular Engineering of a Mammarenavirus with Unbreachable Attenuation

Published:2023-01-31 Issue:1 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Sakabe Saori¹,Cubitt Beatrice¹,Martinez-Sobrido Luis²^ORCID,de la Torre Juan C.¹^ORCID

Affiliation:

1. Department of Immunology and Microbiology, Scripps Research, La Jolla, California, USA

2. Texas Biomedical Research Institute, San Antonio, Texas, USA

Abstract

Several mammarenaviruses cause severe disease in humans and pose important public health problems in their regions of endemicity. Currently, no FDA-licensed mammarenavirus vaccines are available, and anti-mammarenaviral therapy is limited to an off-label use of ribavirin whose efficacy is controversial.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

DOD Peer Reviewed Medical Research Program

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01385-22

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