Rapid Loss of CD4 T Cells by Pyroptosis during Acute SIV Infection in Rhesus Macaques
Author:
Affiliation:
1. Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
2. Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA
Abstract
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
HHS | NIH | NIH Office of the Director
Ragon Institute of MGH, MIT and Harvard
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Link
https://journals.asm.org/doi/pdf/10.1128/jvi.00808-22
Reference31 articles.
1. HIV-1 Directly Kills CD4+ T Cells by a Fas-independent Mechanism
2. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.
3. HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration
4. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
5. Programmed Death of T Cells in HIV-1 Infection
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