Application of Genome-Wide Expression Analysis ToIdentify Molecular Markers Useful in MonitoringIndustrialFermentations

Author:

Higgins Vincent J.12,Rogers Peter J.3,Dawes Ian W.12

Affiliation:

1. Clive and Vera Ramaciotti Centre for Gene Function Analysis

2. School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales 2052

3. Carlton & United Breweries Ltd., Abbotsford, Victoria 3067,Australia

Abstract

ABSTRACT Genome-wide expression analysis of an industrial strain of Saccharomyces cerevisiae identified the YOR387c and YGL258w homologues as highly inducible in zinc-depleted conditions. Induction was specific for zinc deficiency and was dependent on Zap1p. The results indicate that these sequences may be valuable molecular markers for detecting zinc deficiency in industrial fermentations.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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