Evaluation of the Disk Diffusion Method Compared to the Microdilution Method in Susceptibility Testing of Anidulafungin against Filamentous Fungi

Author:

Maida Carmelo Massimo1,Milici Maria Eleonora1,Trovato Laura2,Oliveri Salvatore2,Amodio Emanuele1,Spreghini Elisabetta3,Scalise Giorgio3,Barchiesi Francesco3

Affiliation:

1. Dipartimento di Scienze per la Promozione della Salute-sezione di Microbiologia, Università di Palermo, Palermo, Italy

2. Dipartimento di Scienze Microbiologiche e Scienze Ginecologiche, Università di Catania, Catania, Italy

3. Istituto di Malattie Infettive e Medicina Pubblica, Università Politecnica delle Marche, Ancona, Italy

Abstract

ABSTRACT Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-μg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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