A Safe and Efficient Double-Gene-Deleted Live Attenuated Immersion Vaccine to Prevent the Disease Caused by the Infectious Spleen and Kidney Necrosis Virus

Author:

Zeng Ruoyun1,Pan Weiqiang1,Lin Yifan1,Liang Mincong1,Fu Jiajie1,Weng Shaoping1,He Jianguo1,Guo Changjun12ORCID

Affiliation:

1. State Key Laboratory for Biocontrol, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Marine Sciences, Sun Yat-sen University, Guangzhou, China

2. Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou, Guangdong, China

Abstract

Global aquaculture production reached a record of 122.6 million tons in 2020, with a total value of 281.5 billion U.S. dollars (USD). However, approximately 10% of farmed aquatic animal production is lost due to various infectious diseases, resulting in more than 10 billion USD of economic waste every year.

Funder

Guangdong laboratory for lingnan modern agriculture

MOST | National Key Research and Development Program of China

Guangdong key research and development program

China Agricultural Research System

Guangdong basic and applied basic research foundation

Innovation Group project of Southern Marine Science and Engineering Guangdong Laboratory

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference25 articles.

1. FAO. 2022. The state of world fisheries and aquaculture 2022. Towards blue transformation. FAO, Rome.

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4. Identification of outbreak and infectious diseases pathogen of Siniperca chuatsi;He J;Acta Sci Nat Univ Sunyatseni,1998

5. Non-Targeted UHPLC-Q-TOF/MS-Based Metabolomics Reveals a Metabolic Shift from Glucose to Glutamine in CPB Cells during ISKNV Infection Cycle

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