Enhanced Virus Translation Enables miR-122-Independent Hepatitis C Virus Propagation

Author:

Panigrahi Mamata1,Palmer Michael A.1,Wilson Joyce A.1ORCID

Affiliation:

1. Department of Biochemistry, Microbiology and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Abstract

The unusual and essential role of miR-122 in promoting HCV propagation is incompletely understood. To better understand its role, we have analyzed HCV mutants capable of replicating independently of miR-122.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Canada Foundation for Innovation

University of Saskatchewan

CanHepC

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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