Myeloperoxidase-Cl--H2O2 bactericidal system: effect of bacterial membrane structure and growth conditions

Author:

Rest R F,Spitznagel J K

Abstract

The human-myeloperoxidase-Cl--H2O2 bactericidal system killed (i) smooth Enterobacteria spp. greater than or equal to rough and (ii) static-grown, stationary-phase bacteria greater than or equal to aerated-grown, log-phase. This is in contrast to human neutrophil granule extracts (involved in nonoxidative bactericidal mechanisms) that kill rough and aerated log-phase Enterobacteria spp. much more efficiently.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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