Tuberculosis Treatment Monitoring and Outcome Measures: New Interest and New Strategies

Author:

Heyckendorf Jan1234,Georghiou Sophia B.5,Frahm Nicole6,Heinrich Norbert7,Kontsevaya Irina234,Reimann Maja234,Holtzman David5,Imperial Marjorie8,Cirillo Daniela M.9ORCID,Gillespie Stephen H.10,Ruhwald Morten5ORCID,

Affiliation:

1. Department of Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany

2. Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany

3. German Center for Infection Research (DZIF), Braunschweig, Germany

4. International Health/Infectious Diseases, University of Lübeck, Lübeck, Germany

5. FIND, the Global Alliance for Diagnostics, Geneva, Switzerland

6. Bill & Melinda Gates Medical Research Institute, Cambridge, Massachusetts, USA

7. Division of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich (LMU), Munich, Germany

8. University of California San Francisco, San Francisco, California, USA, United States

9. Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy

10. School of Medicine, University of St Andrews, St Andrews, Fife, Scotland

Abstract

Despite the advent of new diagnostics, drugs and regimens, tuberculosis (TB) remains a global public health threat. A significant challenge for TB control efforts has been the monitoring of TB therapy and determination of TB treatment success.

Funder

Innovative Medicines Initiative

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Reference165 articles.

1. WHO. 2020. Global tuberculosis report. World Health Organization Geneva Switzerland.

2. WHO. 2019. WHO consolidated guidelines on drug-resistant tuberculosis treatment. WHO consolidated guidelines on drug-resistant tuberculosis treatment. World Health Organization Geneva Switzerland.

3. WHO. 2017. Guidelines for treatment of drug-susceptible tuberculosis and patient care (2017 update). World Health Organization Geneva Switzerland.

4. Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis

5. Patient Adherence to Tuberculosis Treatment: A Systematic Review of Qualitative Research

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