Affiliation:
1. Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
2. Deutsches Institut für Ernaehrungsforschung, Abteilung Gastrointestinale Mikrobiologie, 14558 Bergholz-Rehbrücke, Germany
Abstract
ABSTRACT
16S rRNA-targeted oligonucleotide probes were designed for butyrate-producing bacteria from human feces. Three new cluster-specific probes detected bacteria related to
Roseburia intestinalis
,
Faecalibacterium prausnitzii
, and
Eubacterium hallii
at mean populations of 2.3, 3.8, and 0.6%, respectively, in samples from 10 individuals. Additional species-level probes accounted for no more than 1%, with a mean of 7.7%, of the total human fecal microbiota identified as butyrate producers in this study. Bacteria related to
E. hallii
and the genera
Roseburia
and
Faecalibacterium
are therefore among the most abundant known butyrate-producing bacteria in human feces.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference27 articles.
1. The oligonucleotide probe database
2. Phylogenetic Relationships of Butyrate-Producing Bacteria from the Human Gut
3. Bradburn, D. M., J. C. Mathers, A. Gunn, J. Burn, P. D. Chapman, and I. D. Johnston. 1993. Colonic fermentation of complex carbohydrates in patients with familial adenomatous polyposis. Gut34:630-636.
4. Chapman, M. A., M. F. Grahn, M. A. Boyle, M. Hutton, J. Rogers, and N. S. Williams. 1994. Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. Gut35:73-76.
5. Chapman, M. A., M. F. Grahn, M. Hutton, and N. S. Williams. 1995. Butyrate metabolism in the terminal ileal mucosa of patients with ulcerative colitis. Br. J. Surg.82:36-38.
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