Evidence for polymorphonuclear leukocyte collagenase and 92-kilodalton gelatinase in gingival crevicular fluid-Reference-Cited by-同舟云学术

Evidence for polymorphonuclear leukocyte collagenase and 92-kilodalton gelatinase in gingival crevicular fluid

Published:1991-12 Issue:12 Volume:59 Page:4687-4692
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Overall C M¹,Sodek J¹,McCulloch C A¹,Birek P¹

Affiliation:

1. Faculty of Dentistry, University of British Columbia, Vancouver, Canada.

Abstract

Analysis of inflammatory exudate collected from sites of experimental periodontitis in cynomolgus monkeys has revealed the presence of collagenase and a 92-kDa gelatinase that comigrated after electrophoresis with the 92-kDa gelatinase released from polymorphonuclear leukocytes. Since neutralizing antibodies to fibroblast collagenase had no effect on the collagenase activity and bacterial collagenases could not be detected, polymorphonuclear leukocytes appear to be the major source of collagenolytic proteinases in inflammatory fluid from gingiva.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.59.12.4687-4692.1991

Reference51 articles.

1. Improved tests for the evaluation of neutrophil function in human disease;Alexander J. W.;J. Lab. Clin. Med.,1968

2. Measurements of probing velocity with an automated periodontal probe and the relationship with experimental periodontitis in the cynomolgus monkey (Macaca Fascicularis);Birek P.;Arch. Oral. Biol.,1989

3. Monoclonal antibodies to human fibroblast collagenase. Inhibition of enzyme activity, affinity purification of the enzyme, and evidence for clustering of epitopes in the NH2-terminal end of the activated enzyme;Birkedal-Hansen B.;Biochemistry,1988

4. Detergent activation of latent collagenase and resolution of its component molecules;Birkedal-Hansen H.;Biochem. Biophys. Res. Commun.,1982

5. Characterization of collagenolytic activity from strains of Bacteroides gingivalis;Birkedal-Hansen H.;J. Periodontal Res.,1988

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