Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research

Author:

Holguin Leo123ORCID,Echavarria Liliana1,Burnett John C.12ORCID

Affiliation:

1. Center for Gene Therapy, Beckman Research Institute of City of Hope, Duarte, California, USA

2. Irell & Manella Graduate School of Biological Sciences, City of Hope, Duarte, California, USA

3. Center for Comparative Medicine, City of Hope, Duarte, California, USA

Abstract

Currently, there is no cure or vaccine for HIV infection; thus, continued research is needed to end the HIV pandemic. While many animal models are used in HIV research, none is used more than the humanized mouse model.

Funder

California Institute for Regenerative Medicine

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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