Plasmodium falciparum Recrudescence Two Years after Treatment of an Uncomplicated Infection without Return to an Area Where Malaria Is Endemic-Reference-Cited by-同舟云学术

Plasmodium falciparum Recrudescence Two Years after Treatment of an Uncomplicated Infection without Return to an Area Where Malaria Is Endemic

Published:2018-02 Issue:2 Volume:62 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Malvy Denis¹,Torrentino-Madamet Marylin²³⁴,L'Ollivier Coralie⁵⁶,Receveur Marie-Catherine¹,Jeddi Fakhri⁵⁶,Delhaes Laurence⁷,Piarroux Renaud⁵⁶,Millet Pascal⁷,Pradines Bruno²³⁴

Affiliation:

1. Service des Maladies Infectieuses et Tropicales, Hôpital Pellegrin, Bordeaux, France

2. Unité Parasitologie et Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France

3. Aix-Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UM 63, CNRS 7278, IRD 198, INSERM 1095, Institut Hospitalo-Universitaire (IHU) Méditerranée Infection, Marseille, France

4. Centre National de Référence du Paludisme, Marseille, France

5. Laboratoire de Parasitologie, Hôpital la Timone, Marseille, France

6. Aix Marseille Université, Unité Mixte de Recherche MD3, Marseille, France

7. Laboratoire de Parasitologie -Mycologie, Hôpital Pellegrin, CHU de Bordeaux, Bordeaux, France

Abstract

ABSTRACT We report evidence, confirmed by the lack of travel activity outside of France and genetic diversity analysis using polymorphic microsatellite markers, that Plasmodium falciparum malaria infection effectively treated with an artemisinin-based combination can remain dormant and relapse during pregnancy at least 2 years after treatment.

Funder

Santé Publique France

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01892-17

Reference20 articles.

1. ProlongedPlasmodium falciparumInfection in Immigrants, Paris

2. Falciparum Malaria in Patient 9 Years after Leaving Malaria-Endemic Area

3. Microsatellite Markers Reveal a Spectrum of Population Structures in the Malaria Parasite Plasmodium falciparum