Evaluation of the Cepheid Xpert GBS Assay for Rapid Detection of Group B Streptococci in Amniotic Fluids from Pregnant Women with Premature Rupture of Membranes-Reference-Cited by-同舟云学术

Evaluation of the Cepheid Xpert GBS Assay for Rapid Detection of Group B Streptococci in Amniotic Fluids from Pregnant Women with Premature Rupture of Membranes

Published:2013-04 Issue:4 Volume:51 Page:1305-1306
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Bourgeois-Nicolaos Nadege¹,Cordier Anne-Gael²,Guillet-Caruba Christelle¹,Casanova François¹,Benachi Alexandra²,Doucet-Populaire Florence¹³

Affiliation:

1. Service de Bactériologie-Hygiène, Hopital Antoine Béclère, APHP, Université Paris Sud, Clamart, France

2. Service de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Antoine-Béclère, AP-HP, Université Paris Sud, Clamart, France

3. Université Paris Sud, EA 4043 USC INRA, Chatenay-Malabry, France

Abstract

ABSTRACT The Xpert GBS real-time PCR assay for the detection of group B streptococci (GBS) in antepartum screening samples was evaluated on amniotic fluid samples collected from 139 women with premature rupture of membrane at term. When any intrapartum positive result from the Xpert GBS or culture was considered a true positive, the sensitivities of the Xpert GBS and culture were 92.3% and 84.6%, respectively. This assay could enhance exact identification of candidates for intrapartum antibiotic prophylaxis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.03356-12

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