Affiliation:
1. Department of Physiological Chemistry, University of California, Los Angeles 24, California
Abstract
Soboren, Josephine
(University of California, Los Angeles),
and Joseph F. Nyc
. Amino acid interactions in
Neurospora crassa
. J. Bacteriol.
82:
20–25. 1961.—A systematic study of the effects of the naturally occurring amino acids on the growth of a wild-type strain of
Neurospora crassa
focused attention upon
l
-tryptophan, which exhibits a strong growth inhibitory effect. Further investigation disclosed that other tryptophan metabolites, anthranilic acid, indole, kynurenine, and 3-hydroxykynurenine also inhibit growth. The proposed antimetabolic role of these aromatic compounds explains the poor growth response of certain tryptophan-requiring strains of
N. crassa
to tryptophan supplements. The growth of normal and mutant strains of
N. crassa
on media supplemented with tryptophan is influenced by the presence of other amino acids.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
9 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献