Affiliation:
1. National Health Research Institutes, Zhunan, Taiwan
2. TaiGen Biotechnology Co., Ltd., Taipei, Taiwan
Abstract
ABSTRACT
The
in vitro
antibacterial activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, against 770 clinical isolates were investigated. Nemonoxacin (tested as its malate salt, TG-875649) showed better
in vitro
activity than ciprofloxacin and levofloxacin against different species of staphylococci, streptococci, and enterococci,
Neisseria gonorrhoeae
, and
Haemophilus influenzae
. The
in vitro
activity of TG-875649 was also comparable to or better than that of moxifloxacin against these pathogens, which included ciprofloxacin-resistant, methicillin-resistant
Staphylococcus aureus
and levofloxacin-resistant
Streptococcus pneumoniae
.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
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