High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria-Reference-Cited by-同舟云学术

High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria

Published:2022-06-21 Issue:6 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Tamaki Fabio¹,Fisher Fabio²,Milne Rachel¹,Terán Fernando Sánchez-Román²,Wiedemar Natalie¹,Wrobel Karolina¹,Edwards Darren¹,Baumann Hella²,Gilbert Ian H.¹^ORCID,Baragana Beatriz¹,Baum Jake²³,Wyllie Susan¹^ORCID

Affiliation:

1. Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom

2. Department of Life Sciences, Imperial College London, London, United Kingdom

3. School of Medical Sciences, University of New South Wales, New South Wales, Sydney, Australia

Abstract

Artemisinin-based combination therapies have been crucial in driving down the global burden of malaria, the world’s largest parasitic killer. However, their efficacy is now threatened by the emergence of resistance in Southeast Asia and sub-Saharan Africa.

Funder

Medicines for Malaria Venture

UKRI | Medical Research Council

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.00237-22

Reference49 articles.

1. World Trade Report 2019