In Vitro Activities of the Glycylcycline GAR-936 against Gram-Positive Bacteria

Author:

Boucher Helen W.12,Wennersten Christine B.1,Eliopoulos George M.12

Affiliation:

1. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215,1and

2. Harvard Medical School, Boston, Massachusetts 021152

Abstract

ABSTRACT The in vitro activities of GAR-936, the 9- t -butylglycylamido derivative of minocycline, were compared with those of doxycycline, minocycline, and tetracycline against 527 gram-positive clinical isolates. GAR-936 inhibited all strains, including those resistant to other tetracyclines, at concentrations of ≤2 μg/ml, except two strains of JK diphtheroids for which the MIC was 4 μg/ml.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference16 articles.

1. Nosocomial enterococci resistant to vancomycin—United States, 1989–1993.;Centers for Disease Control and Prevention;Morb. Mortal. Wkly. Rep.,1993

2. In vitro activity of RP59500, an injectable streptogramin antibiotic, against vancomycin-resistant gram-positive organisms

3. Vancomycin-resistant enterococcal bacteremia: natural history and attributable mortality.;Edmond M. B.;Clin. Infect. Dis.,1996

4. In vitro activity of Sch 29482 in comparison with other oral antibiotics.;Eliopoulos G. M.;J. Antimicrob. Chemother.,1982

5. In vitro activities of two glycylcyclines against gram-positive bacteria

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