Identification of a ROB-1 beta-lactamase in Haemophilus ducreyi-Reference-Cited by-同舟云学术

Identification of a ROB-1 beta-lactamase in Haemophilus ducreyi

Published:1992-02 Issue:2 Volume:36 Page:467-469
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Maclean I W¹,Slaney L¹,Juteau J M¹,Levesque R C¹,Albritton W L¹,Ronald A R¹

Affiliation:

1. Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.

Abstract

A collection of 100 clinical isolates of Haemophilus ducreyi from Thailand were all found to harbor a 5.4-kb plasmid, designated pTH126, which was shown to contain the bla ROB-1 gene. Restriction enzyme analysis and DNA-DNA hybridization studies confirmed that pTH126 was similar to the ROB-1 beta-lactamase plasmid pVM105 from Actinobacillus pleuropneumoniae. In approximately one-half of the isolates, pTH126 was found together with pHD131, which mediates TEM-1 beta-lactamase production.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.36.2.467

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