Affiliation:
1. Antimicrobial Agents Research Group, Division of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom
Abstract
ABSTRACT
Simultaneous overexpression of MexAB-OprM and MexEF-OprN was demonstrated for a multiply antibiotic-resistant clinical isolate of
Pseudomonas aeruginosa
(G49). G49 also had decreased expression of OprF. No mutations in
mexR
or its upstream promoter region,
mexT
,
oprM
,
oprF
, or
sigX
were revealed, suggesting regulation by a hitherto undescribed locus.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
54 articles.
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