Control of Candida albicans Murine Vaginitis by Topical Administration of Polycarbophil-Econazole Complex-Reference-Cited by-同舟云学术

Control of Candida albicans Murine Vaginitis by Topical Administration of Polycarbophil-Econazole Complex

Published:1998-09 Issue:9 Volume:42 Page:2434-2436
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ghelardi E.¹,Tavanti A.¹,Lupetti A.¹,Celandroni F.¹,Boldrini E.²,Campa M.¹,Senesi S.¹

Affiliation:

1. Dipartimento di Biomedicina Sperimentale, Infettiva e Pubblica, Università degli Studi di Pisa,1 and

2. Farmigea S.p.A.,2 56127 Pisa, Italy

Abstract

ABSTRACT The complexation of econazole with the mucoadhesive polycarbophil was found to significantly improve the therapeutic benefit of the drug in the topical treatment of experimental vaginal candidiasis in mice, while no difference in the antimycotic activity exerted by econazole and polycarbophil-econazole could be detected in vitro.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.42.9.2434

Reference22 articles.

1. Adsorption from the vagina.;Benzinger D. P.;Drug Metab. Rev.,1983

2. Bergh P. A. Vaginal changes with aging The gynecologist and the older patient. Breen J. L. 1988 299 311 Aspen Publishers Rockville Md

3. Novel vaginal drug release application.;Brannon-Peppas L.;Adv. Drug Delivery Rev.,1993

4. Pharmaceutical and medical aspects of bioadhesive system for drug administration.;Duchene D.;Drug Dev. Ind. Pharm.,1988

5. Candida-specific cell-mediated immunity is demonstrable in mice with experimental vaginal candidiasis

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Efficacy of Solanum torvum Sw. as a Potential Antifungal Medicinal Plant against Candida albicans in In Vitro and In Vivo Experimental Models;Indian Journal of Pharmaceutical Sciences;2022

2. Vaginal Bioadhesive Drug Delivery Systems and Their Applications;Bioadhesives in Drug Delivery;2020-05-22

3. Role of chitosan on controlling the characteristics and antifungal activity of bioadhesive fluconazole vaginal tablets;Saudi Pharmaceutical Journal;2018-02

4. Mucoadhesion: A promising approach in drug delivery system;Reactive and Functional Polymers;2016-03

5. Drug Delivery: Intravaginal, Advantages and Challenges;Encyclopedia of Biomedical Polymers and Polymeric Biomaterials;2016-01-26