Interaction between Antibiotic Resistance, Resistance Genes, and Treatment Response for Urinary Tract Infections in Primary Care-Reference-Cited by-同舟云学术

Interaction between Antibiotic Resistance, Resistance Genes, and Treatment Response for Urinary Tract Infections in Primary Care

Published:2019-09 Issue:9 Volume:57 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Ho Hanley J.¹,Tan Mei Xuan²,Chen Mark I.²³^ORCID,Tan Thean Yen⁴,Koo Seok Hwee⁵,Koong Agnes Y. L.⁶⁷,Ng Lok Pui⁶⁷,Hu Pei Lin⁶⁷,Tan Kee Tung⁶,Moey Peter K. S.⁶⁷,Koh Eileen Y. L.⁶,Wong Chia Siong¹,Lye David C.²,Tan Ngiap Chuan⁶⁷

Affiliation:

1. Department of Clinical Epidemiology, Office of Clinical Epidemiology, Analytics, and Knowledge, Tan Tock Seng Hospital, Singapore

2. Infectious Disease Research and Training Office, National Centre for Infectious Diseases, Singapore

3. Saw Swee Hock School of Public Health, National University of Singapore, Singapore

4. Department of Laboratory Medicine, Changi General Hospital, Singapore

5. Clinical Trials and Research Unit, Changi General Hospital, Singapore

6. SingHealth Polyclinics, Singapore

7. SingHealth-Duke NUS Family Medicine Academic Clinical Programme, Duke-NUS Medical School, Singapore

Abstract

Given increasing antimicrobial resistance, we aimed to determine antibiotic susceptibility and presence of resistance genes in uropathogens in primary care, factors associated with resistance to commonly prescribed antibiotics, and effect of treatment on early symptom resolution. We conducted a prospective study of primary care patients with urinary tract infection (UTI) symptoms and culture-confirmed UTI in Singapore from 2015 to 2016.

Funder

MOH | National Medical Research Council

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00143-19

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