Effects of roxithromycin and erythromycin on interleukin 8-induced neutrophil recruitment and goblet cell secretion in guinea pig tracheas-Reference-Cited by-同舟云学术

Effects of roxithromycin and erythromycin on interleukin 8-induced neutrophil recruitment and goblet cell secretion in guinea pig tracheas

Published:1996-07 Issue:7 Volume:40 Page:1726-1728
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Tamaoki J¹,Nakata J¹,Tagaya E¹,Konno K¹

Affiliation:

1. First Department of Medicine, Tokyo Women's Medical College, Japan.

Abstract

Inhaled interleukin 8 caused an increase in goblet cell secretion in guinea pig tracheas, which was accompanied by mucosal infiltration of neutrophils. These responses were inhibited by pretreatment with roxithromycin or erythromycin in a dose-dependent fashion. Macrolides may thus be a value in protecting against neutrophil-associated airway hypersecretion.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.40.7.1726

Reference10 articles.

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