Diagnostic Performance of the Novel BioPlex Lyme Serological Assays in European Patients with Lyme Disease

Author:

Baarsma M. E. (Ewoud)1ORCID,Ursinus Jeanine1,Zaaijer Hans L.2,Kuiper Herman34,Hovius Joppe W.1

Affiliation:

1. Amsterdam UMC, University of Amsterdam, Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam, the Netherlands

2. Sanquin Research, Department of Blood‐borne Infections, Amsterdam, the Netherlands

3. Amsterdam UMC, University of Amsterdam, Department of Medical Microbiology, Amsterdam, the Netherlands

4. Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam, the Netherlands

Abstract

Serodiagnosis of Lyme borreliosis (LB) comes with several drawbacks, among which is limited sensitivity in early disease. This study assesses the sensitivity and specificity of the novel BioPlex 2200 Lyme IgG and Lyme IgM assays.

Funder

European Union Regional Development Fund

Bio-Rad Laboratories

ZonMw

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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