Affiliation:
1. Memorial Sloan-Kettering Cancer Center, New York, New York 10021
Abstract
The theory of Caspar and Klug (1962) for the structure of isometric viruses has been generalized to the case in which the identical repeating unit is composed of
n
nonidentical polypeptide chains. This modified theory accounts for the structure of picornaviruses, the lambda phage head, cowpea mosaic virus, and φX174, while at the same time conserving the principle of having identical subunits in identical environments. Furthermore, the modified theory suggests amending the triangulation number to
T
[
n
] for capsids with
n
nonidentical polypeptide chains as the repeating unit.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
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