Coexistence ofmcr-1andblaNDM-1in Escherichia coli from Venezuela-Reference-Cited by-同舟云学术

Coexistence ofmcr-1andblaNDM-1in Escherichia coli from Venezuela

Published:2016-07-18 Issue:10 Volume:60 Page:6356-6358
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob. Agents Chemother.

Author:

Delgado-Blas Jose F.,Ovejero Cristina M.,Abadia-Patiño Lorena,Gonzalez-Zorn Bruno

Abstract

ABSTRACTWe studied the presence of the mobile colistin resistance genemcr-1in human, animal, and environmentalEnterobacteriaceaesamples from Cumana, Venezuela, that were collected in 2015. Themcr-1gene was detected in 2/93Escherichia coliisolates from swine (novel ST452) and human (ST19) samples that were resistant to colistin. Whole-genome sequencing and transformation experiments identifiedmcr-1on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes.

Funder

European Commission (EC)

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference14 articles.

1. Extensively drug-resistant carbapenemase-producing Enterobacteriaceae: an emerging challenge for clinicians and healthcare systems;J Intern Med,2015

2. Use of colistin-containing products within the European Union and European Economic Area (EU/EEA): development of resistance in animals and possible impact on human and animal health;Int J Antimicrob Agents,2015

3. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study;Lancet Infect Dis,2016

4. Skov RL, Monnet DL. 2016. Plasmid-mediated colistin resistance (mcr-1 gene): three months later, the story unfolds. Euro Surveill 21(9):pii=30155. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=21403.

Cited by 105 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Detecting Class 1 Integrons and Their Variable Regions in Escherichia coli Whole-Genome Sequences Reported from Andean Community Countries;Antibiotics;2024-04-25

2. Molecular Detection of Plasmid-mediated colistin-resistance genes in Multi-drug resistant Escherichia coli isolated from human and poultry in Duhok city, Iraq;Egyptian Journal of Veterinary Sciences;2024-03-01

3. Resistance mechanisms for Gram-negative bacteria-specific lipopeptides, turnercyclamycins, differ from that of colistin;Microbiology Spectrum;2023-12-12

4. Situation Report on mcr-Carrying Colistin-Resistant Clones of Enterobacterales: A Global Update Through Human-Animal-Environment Interfaces;Current Microbiology;2023-11-21

5. Isolation and Characterization of Carbapenem-Resistant Escherichia coli Carrying blaNDM and mcr-1 from Recurrent Urinary Tract Infection Patient;Canadian Journal of Infectious Diseases and Medical Microbiology;2023-08-30