Cross-Genus “Boot-Up” of Synthetic Bacteriophage in Staphylococcus aureus by Using a New and Efficient DNA Transformation Method-Reference-Cited by-同舟云学术

Cross-Genus “Boot-Up” of Synthetic Bacteriophage in Staphylococcus aureus by Using a New and Efficient DNA Transformation Method

Published:2022-02-08 Issue:3 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Assad-Garcia Nacyra¹,D’Souza Roshan²^ORCID,Buzzeo Rachel²,Tripathi Arti¹,Oldfield Lauren M.¹^ORCID,Vashee Sanjay¹^ORCID,Fouts Derrick E.²^ORCID

Affiliation:

1. Synthetic Biology and Bioenergy, The J. Craig Venter Institute, Rockville, Maryland, USA

2. Genomic Medicine, The J. Craig Venter Institute, Rockville, Maryland, USA

Abstract

The continued emergence of antibiotic-resistant bacterial pathogens has heightened the urgency for alternative antibacterial strategies. Phages provide an alternative treatment strategy but are difficult to optimize.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Defense

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01486-21

Reference85 articles.

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4. Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection

5. Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

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