Dogs of Nomadic Pastoralists in Northern Kenya Are Reservoirs of Plasmid-Mediated Cephalosporin- and Quinolone-Resistant Escherichia coli, Including Pandemic Clone B2-O25-ST131

Author:

Albrechtova Katerina1,Dolejska Monika12,Cizek Alois32,Tausova Dagmar1,Klimes Jiri1,Bebora Lily4,Literak Ivan12

Affiliation:

1. Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic

2. CEITEC VFU, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic

3. Institute of Microbiology and Infectious Diseases, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic

4. Department of Veterinary Pathology, Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Nairobi, Kapenguria Road, Nairobi, Kenya

Abstract

ABSTRACT Resistance in Escherichia coli isolates colonizing gastrointestinal tracts of dogs, cats, and their owners in Northern Kenya was investigated with an emphasis on extended-spectrum beta-lactamases (ESBLs). Totals of 47 (22%, n = 216), 2 (4%, n = 50), and 4 (17%, n = 23) CTX-M-15-producing E. coli isolates were obtained from dogs, cats, and humans, respectively. CTX-M-15-producing E. coli isolates with identical PFGE profiles were detected in animals and humans living in the same area.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference17 articles.

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3. Identification of plasmids by PCR-based replicon typing;Caratolli A;J. Microbiol. Methods,2005

4. CDC. 2004. Standardized molecular subtyping of foodborne bacterial pathogens by pulse-field gel electrophoresis. Centers for Disease Control Atlanta GA.

5. Dogs can play useful role as sentinel hosts for disease;Cleaveland S;Nature,2006

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