Population Pharmacokinetics of Amikacin in Adult Patients with Cystic Fibrosis

Author:

Illamola Sílvia M.1,Huynh Hoa Q.2,Liu Xiaoxi1,Bhakta Zubin N.3,Sherwin Catherine M.12,Liou Theodore G.345ORCID,Carveth Holly34,Young David C.23

Affiliation:

1. Division of Clinical Pharmacology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, USA

2. University of Utah College of Pharmacy, Salt Lake City, Utah, USA

3. The Adult Cystic Fibrosis Center, University of Utah, Salt Lake City, Utah, USA

4. Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, USA

5. The Center for Quantitative Biology, University of Utah, Salt Lake City, Utah, USA

Abstract

Practitioners commonly use amikacin in patients with cystic fibrosis. Establishment of the pharmacokinetics of amikacin in adults with cystic fibrosis may increase the efficacy and safety of therapy.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference43 articles.

1. Cystic fibrosis: Insight into CFTR pathophysiology and pharmacotherapy

2. Cystic fibrosis

3. Pathology of cystic fibrosis review of the literature and comparison with 146 autopsied cases;Oppenheimer EH;Perspect Pediatr Pathol,1975

4. Pulmonary complications of cystic fibrosis;Flume PA;Respir Care,2009

5. Management of Pulmonary Disease in Patients with Cystic Fibrosis

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