Value of whole-cell antigen extracts for serologic detection of Helicobacter pylori

Author:

Salama S M1,Wefuan J N1,Shiro-Koulla S1,Mbakop A1,Tagni-Sartre M1,Ndam E C1,Ngu J L1,Taylor D E1

Affiliation:

1. Department of Medical Microbiology and Infectious Diseases, University of Alberta, Edmonton, Canada.

Abstract

Whole-cell protein extracts of Helicobacter pylori strains were evaluated by enzyme-linked immunosorbent assay to detect immunoglobulin G antibody against H. pylori in 113 patients with upper gastrointestinal complaints. These antigen preparations were of value for detecting infection by H. pylori in patients with high antibody titers (> or = 12,800), whereas for patients with lower titers, the results were inconclusive.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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