Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS-Reference-Cited by-同舟云学术

Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS

Published:1993-10 Issue:10 Volume:31 Page:2824-2827
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Mazzulli T¹,Rubin R H¹,Ferraro M J¹,D'Aquila R T¹,Doveikis S A¹,Smith B R¹,The T H¹,Hirsch M S¹

Affiliation:

1. Infectious Disease Unit, Massachusetts General Hospital, Boston.

Abstract

We evaluated a rapid immunoperoxidase technique for the detection of cytomegalovirus (CMV) antigenemia in peripheral blood neutrophils of 56 transplant recipients (117 specimens) and 36 persons with AIDS (59 specimens). Antigenemia was 92% sensitive and 98% specific for the detection of clinical CMV infection in transplant recipients and 100% sensitive and 86% specific in persons with AIDS. Overall, CMV antigenemia was a more rapid and sensitive method for the detection of clinical CMV infection than either shell vial culture or conventional tube culture of blood.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.31.10.2824-2827.1993

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