Enhanced Interferon Response to Murine Leukemia Virus by Ascorbic Acid

Author:

Siegel Benjamin V.1

Affiliation:

1. Department of Pathology, University of Oregon Medical School, Portland, Oregon 97201

Abstract

BALB/cJ mice, on an ad libitum regimen of 250 mg% l -ascorbate in their drinking water, displayed augmented levels of circulating interferon after stimulation with murine leukemia virus.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference11 articles.

1. Vitamin C and immunity;Bourne G. H.;Brit. J. Nutr.,1949

2. Production en masse, purification partielle et caracterisation d'un interferon destine a des essais therapeutique humains;Falcoff E.;Ann. Inst. Pasteur Paris,1966

3. Dye uptake methods for assessing viral cytopathogenicity and their application to interferon assays;Finter N. B.;J. Gen. Virol.,1969

4. Interferon and murine leukemia. V. Effect of interferon preparations on the evolution of Rauscher disease in mice;Gresser I.;J. Nat. Cancer Inst.,1968

5. Interferon and murine leukemia. I. Inhibitory effect of interferon preparations on development of Friend leukemia in mice;Gresser I.;Proc. Soc. Exp. Biol. Med.,1967

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