The value of observational registry studies for the next infectious disease emergency

Author:

Senefeld Jonathon W.1ORCID,Marks Peter2,Casadevall Arturo3ORCID,Joyner Michael J.4

Affiliation:

1. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

2. Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA

3. Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

4. Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA

Abstract

ABSTRACT During infectious disease emergencies, it may be necessary to deploy new therapies without conclusive evidence for their effectiveness. During the SARS-CoV-2 pandemic, several countries used registries to track the use of COVID-19 convalescent plasma (CCP). Those registries provided evidence that CCP was effective when used early and with high titer.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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