Author:
Mehta R J,Nash C H,Bozzola J J
Abstract
The antifungal agent Aculeacin A at subinhibitory levels induced lytic plaques in lawns of Candida albicans. Electron microscopic examination of plaque lysates suspended in phosphotungstic acid revealed the presence of spherical particles 12, 18, and 28 to 30 nm in size. Particles were also found in ultrathin sections of treated C. albicans cells. The plaque lysate lost infectivity after treatment with UV light, heat treatment at 80 degrees C for 10 min, or being held at pH 2 for 30 min.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference4 articles.
1. Viruses of eukaryotic microorganisms. Annu;Lemke P.;Rev. Microbiol.,1976
2. Lemke P. 1979. Viruses and plasmids in fungi p. 325-362. Marcel Dekker Inc. New York.
3. On the mode of action of new antifungal antibiotic;Mizoguchi J.;Aculeacin A. J. Antibiot.,1977
4. Viruslike particles in Candida tropicalis;Nesterova G. F.;Microbiology,1973
Cited by
9 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献