Treatment Failure of Nosocomial Pertussis Infection in a Very-Low-Birth-Weight Neonate

Author:

Bonacorsi Stéphane1,Farnoux Caroline2,Bidet Philippe1,Caro Valérie3,Aizenfisz Sophie4,Benhayoun Mounir4,Aujard Yannick2,Guiso Nicole3,Bingen Edouard1

Affiliation:

1. Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA 3105), Université Denis Diderot-Paris 7, Service de Microbiologie

2. Service de Néonatologie

3. Centre National de Référence de la Coqueluche et autres Bordetelloses, Institut Pasteur, 75015 Paris, France

4. Service de Réanimation, Hôpital Robert Debré (AP-HP), 75019 Paris, France

Abstract

ABSTRACT We describe a case of nosocomial maternal transmission of Bordetella pertussis to a very-low-birth-weight (VLBW) neonate in whom treatment was unsuccessful. This case underscores the need for rapid and sensitive PCR diagnosis in VLBW neonates and in parents with clinical signs of pertussis and suggests that standard treatment may not be appropriate for VLBW neonates.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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