In Vitro Activities of the New Ketolide HMR 3647 (Telithromycin) in Comparison with Those of Eight Other Antibiotics against Viridans Group Streptococci Isolated from Blood of Neutropenic Patients with Cancer-Reference-Cited by-同舟云学术

In Vitro Activities of the New Ketolide HMR 3647 (Telithromycin) in Comparison with Those of Eight Other Antibiotics against Viridans Group Streptococci Isolated from Blood of Neutropenic Patients with Cancer

Published:2001-02 Issue:2 Volume:45 Page:624-626
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Alcaide Fernando¹,Benı́tez Miguel Angel¹,Carratalà Jordi²,Gudiol Francesc²,Liñares Josefina¹,Martı́n Rogelio¹

Affiliation:

1. Departments of Microbiology1 and

2. Infectious Diseases,2 Hospital “Prı́nceps d'Espanya,” Ciutat Sanitària i Universitària de Bellvitge, 08907 L'Hospitalet de Llobregat, Barcelona, Spain

Abstract

ABSTRACT The in vitro activities of the ketolide telithromycin and eight other antibiotics were tested against 77 strains of viridans group streptococci isolated from blood samples of neutropenic patients. Thirty-one (40.3%) of the strains were resistant to penicillin G, and 27 (35.1%) were resistant to erythromycin A. Telithromycin (MIC range of ≤0.03 to 1 μg/ml) was the most active antimicrobial tested. These data suggest that telithromycin could be useful for treatment of viridans group streptococcal bacteremia in neutropenic patients with cancer.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.45.2.624-626.2001

Reference30 articles.

1. In vitro activities of 22 beta-lactam antibiotics against penicillin-resistant and penicillin-susceptible viridans group streptococci isolated from blood

2. In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin-dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients

3. Streptococcal and enterococcal bacteremia in patients with cancer.;Awada A.;Clin. Infect. Dis.,1992

4. In Vitro Activities of the Ketolide HMR 3647 against Recent Gram-Positive Clinical Isolates and Haemophilus influenzae

5. Streptococcus viridans bacteremia following autologous peripheral blood stem cell transplantation.;Bilgrami S.;Bone Marrow Transplant.,1998

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