Environmental Dependence of Competitive Fitness in Rifampin-Resistant <i>rpoB</i> Mutants of Bacillus subtilis-Reference-Cited by-同舟云学术

Environmental Dependence of Competitive Fitness in Rifampin-Resistant rpoB Mutants of Bacillus subtilis

Published:2022-03-08 Issue:5 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Leehan Joss D.¹,Nicholson Wayne L.¹^ORCID

Affiliation:

1. Department of Microbiology and Cell Science, University of Florida, Merritt Island, Florida, USA

Abstract

Microbial resistance to antibiotics is a growing threat to public health across the world. Historically, resistance to antibiotics has been associated with reduced fitness.

Funder

National Aeronautics and Space Administration

U.S. Department of Agriculture

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.02422-21

Reference63 articles.

1. Interaction of rifamycin with bacterial RNA polymerase.

2. Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns

3. Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistance

4. Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase

5. The β′ Subunit of Escherichia coli RNA Polymerase Is Not Required for Interaction with Initiating Nucleotide but Is Necessary for Interaction with Rifampicin

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2. Mutations in rpoB That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility;mBio;2023-04-25

3. Mutations inrpoBthat confer rifampicin resistance can alter levels of peptidoglycan precursors and affect β-lactam susceptibility;2022-11-15