Emergence of Enterobacteriaceae Isolates Producing CTX-M Extended-Spectrum β-Lactamase in Austria

Author:

Eisner Alexandra1,Fagan Elizabeth J.2,Feierl Gebhard1,Kessler Harald H.1,Marth Egon1,Livermore David M.2,Woodford Neil2

Affiliation:

1. Institute of Hygiene, Medical University of Graz, 8010 Graz, Austria

2. Antibiotic Resistance Monitoring and Reference Laboratory, Centre for Infections, London NW9 5HT, United Kingdom

Abstract

ABSTRACT Among 149 extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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